Creatine and Uric acid levels are lower than normal, at least in women.  Ex vivo CD4(+) T cells isolated from the circulation show a wrong TIM -3 (Immunoregulation) behavior,  and relapses are associated with CD8(+) T Cells .  There is a set of differentially expressed genes between MS and healthy subjects in peripheral blood T cells from clinically active MS patients. There are also differences between acute relapses and complete remissions.  Platelets are known to have abnormal high levels.