In the long-term study in subjects with schizoaffective disorder, the EPS during the 25-week open-label INVEGA SUSTENNA® treatment were hyperkinesia (%), parkinsonism (%), tremor (%), dyskinesia (%), and dystonia (%). During the 15-month double-blind treatment, the incidence of any EPS was similar to that of the placebo group (% and % respectively). The most commonly reported treatment-emergent EPS-related adverse events ( > 2%) in any treatment group in the double-blind phase of the study (INVEGA SUSTENNA® versus placebo) were hyperkinesia (% vs. %), parkinsonism (% vs. %), and tremor (% vs. %).
Infectious (septic) bursitis requires even further evaluation and aggressive treatment. The bursal fluid can be examined in the laboratory to identify the microbes causing the infection. Septic bursitis requires antibiotic therapy, sometimes intravenously. Repeated aspiration of the infected fluid may be required. Surgical drainage and removal of the infected bursa sac (bursectomy) may also be necessary. Generally, the adjacent joint functions normally after the surgical wound heals. If treatment is delayed, complications include damage to the adjacent joint or spread of infection.