The broad take-away here, if there is one, is that there is no perfect medication , no matter how wondrous its short- and long-term health benefits might appear on paper. For instance, though NSAIDs may trump acetaminophen in effectiveness, they also — very slightly — raise your risk of heart attack and stroke . And nearly 500 Americans are estimated to die from acetaminophen overdoses every year. None of this means you shouldn’t take a pill for your headache when it comes roaring by, it just means staying aware of that pill’s potential strengths and weaknesses.
In many countries, OTC or non-prescription drugs are selected by a regulatory agency so as to check the ingredients that are used in the making of drugs are safe and effective when used without a doctor's advise. These non-prescription drugs are usually regulated by active pharmaceutical ingredients (APIs), not final products. This implies that the governments allow drugs manufacturers the right to formulate ingredients, or combinations of ingredients, to make proper medicinal mixtures. Regulations related to who is authorized to dispense these drugs, to where they are to be sold, and whether a prescription is required vary considerably from country to country. In India. all the drugs that are not included in the list of prescription drugs are considered as non-prescription drugs (or OTC drugs).
Prescription NSAIDs are an important treatment for the symptoms of many debilitating conditions, including osteoarthritis, rheumatoid arthritis, gout and other rheumatological and painful conditions. OTC NSAIDs are used to temporarily reduce fever and to treat minor aches and pains such as headaches, toothaches, backaches, muscular aches, tendonitis, strains, sprains and menstrual cramps. Common OTC NSAIDs include ibuprofen (Motrin, Advil) and naproxen (Aleve). In addition, some combination medicines that relieve various symptoms, such as multi-symptom cold products, contain NSAIDs.