There is inadequate evidence of safety in human pregnancy. Administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate and intra-uterine growth retardation. There may therefore, be a risk of such effects in the human foetus. It should be noted, however, that the foetal changes in animals occur after relatively high systemic exposure. Beclometasone dipropionate is delivered directly to the lungs by the inhaled route and so avoids the high level of exposure that occurs when corticosteroids are given by systemic routes.
Qvar's Aerosol inhaler is a standard inhaler device – when the metal canister is pressed down, the medicine is released as a spray. This requires that you time your inhalation correctly, so it is worth checking frequently with your GP or nurse to make sure that your technique is correct. The second option is the Qvar Autohaler. Once primed, this type of inhaler automatically releases the dosage when you inhale from the mouthpiece. This may be preferable for you if, for any reason, you find it difficult to coordinate pressing down the canister with inhaling. Both types of the inhaler are available in strengths of 50 or 100 micrograms. Your doctor will prescribe the strength appropriate for you.
National Jewish Medical and Research Center: "Inhaled Medication with a Metered Dose Inhaler (MDI)."
Asthma Society of Canada: "How to Use Your Inhaler."
Science Daily: "New Asthma Inhaler Propellant Effective, But Costlier."
American College of Chest Physicians: "Using Your MDI-Closed Mouth Technique, Patient Education Guide."
American Academy of Allergy, Asthma & Immunology (AAAAI): "Cumulative effects of formoterol administered by a dry powder inhaler;" "Inhalers;" and "Anti-inflammatory effects of inhaled steroids delivered by HFA-MDI vs delivery by dry powder inhaler."
News release, Merck.
Boehringer Ingelheim: "US FDA Expands Approval of Tiotropium Respimat® for Maintenance Treatment of Asthma in Children."
FDA. Prescribing Information: Spiriva Respimat.