If you are or will be breast-feeding while you use hydrocortisone cream, check with your doctor. Discuss any possible risks to your baby. Possible side effects of hydrocortisone cream: All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Burning, dryness, itching, or mild skin irritation. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue ; acne-like rash; excessive hair growth; inflamed hair follicles; inflammation around the mouth; itching, burning, pain, redness, or swelling of the skin not present before using hydrocortisone cream; muscle weakness; symptoms of high blood sugar eg, increased thirst, hunger, or urination; confusion; unusual drowsiness; flushing; rapid breathing ; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.
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