Taking both a steroid and aspirin can greatly increase your risk of developing a stomach ulcer. If you take this combination of medicines it is commonly advised that you also take a medicine to reduce the acid in your stomach. The aim is to prevent the serious complication of a bleeding stomach ulcer from developing. PPIs are a group (class) of medicines that work on the cells that line the stomach, reducing the production of acid. They include esomeprazole , lansoprazole , omeprazole , pantoprazole and rabeprazole . They come in various different brand names. One of these will normally be advised if you take a steroid and aspirin.
At present, prednisone remains the standard of care for GCA. While it works very well, there are many side-effects of this medication. Other immune suppressing medications have been tried but do not work very well for this condition. Methotrexate, a medication commonly used for treatment of rheumatoid arthritis, is sometimes used to help reduce the risk of disease flares. Other treatments are currently being investigated. The types of inflammatory cells that are involved in the arteritis are being identified in current research. Understanding the nature of the inflammatory processes may lead to improved treatment.