Anabolic steroid abuse can result in permanent damage to the heart, liver, and kidneys. In males, steroid abuse can decrease sperm production, shrink the testicles, cause impotence, and produce irreversible breast enlargement (gynecomastia). Females can develop more masculine characteristics such as deepening of the voice and excessive body hair. In adolescents, abuse of anabolic steroids can stunt bone growth, reducing maximum height potential. Other side effects include acne, cysts, and oily hair and skin. Additionally, individuals who inject anabolic steroids with nonsterile needles risk developing HIV and other blood-borne infections.*
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Epidural injections are often used to treat radicular pain, also called sciatica , which is pain that radiates from the site of a pinched nerve in the low back to the area of the body aligned with that nerve, such as the back of the leg or into the foot. Inflammatory chemicals (. substance P, PLA2, arachidonic acid, TNF-α, IL-1, and prostaglandin E2) and immunologic mediators can generate pain and are associated with common back problems such as lumbar disc herniation or facet joint arthritis . These conditions, as well as many others, provoke inflammation that in turn can cause significant nerve root irritation and swelling.