Why do steroids cause high blood pressure

At least one study reports the onset of personality changes, including increased alcohol consumption, after the use of steroids, but notes that the degree of violence experienced was markedly more severe than in previous episodes in which only alcohol was implicated (Conacher 1989) Wesley had supposedly been sober since his treatment at Briarwood in 1986, but began drinking again as his steroid abuse increased. Several other studies indicate that depression and suicidal ideation often accompany the feelings of uncontrollable violence and paranoia experienced by steroid users (Perry 1997). In fact, testosterone, which was once used to treat depression is now known to cause it (Corrigan 1996).

A league of their own: demographics, motivations and patterns of use of 1,955 male adult non-medical anabolic steroid users in the United States.  Cohen, et al. 2007.
Adverse health effects of anabolic androgenic steroids.  Amsterdam, et al. 2010.
Anabolic steroid abuse: Psychiatric and physical costs.  Talih, et al. 2007.
Pharmacology of anabolic steroids.  Kicman. 2008. 
Social capital: Implications from an investigation of illegal anabolic  steroid networks.  Maycock, et al. 2007.
Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activities: Applied modifications in the steroidal structure.  Fragkaki, et al. 2009. 
Control of Human Sebocyte Proliferation in Vitro by Testosterone and 5-DHT is Dependent on the Localization of the Sebaceous Glands.  Akamatsu, et al. 1992.

“High-dose cortisone is the second most common cause of osteoporosis, and we currently have no real treatment for this serious side effect,” says senior author Steven L. Teitelbaum, ., Messing Professor of Pathology and Immunology. “Given how frequently these drugs are used to treat many different conditions, that’s a major clinical problem.”
Teitelbaum and colleagues including lead author Hyun-Ju Kim, ., a postdoctoral fellow, publish their results in the August issue of the Journal of Clinical Investigation …
Earlier attempts to identify the connection between bone loss and cortisone produced seemingly contradictory results. In lab animal experiments, researchers found cortisone caused bone-building osteoblast cells to self-destruct, suggesting that cortisone disrupts the body’s ability to form new bone after it is naturally dismantled by osteoclasts. However, experiments in the test tube also showed cortisone stimulates bone formation.
Teitelbaum identified a new opportunity for exploring the conundrum while at a lecture by Washington University colleague Louis J. Muglia, ., ., director of pediatric endocrinology at St. Louis Children’s Hospital. Muglia’s group studies the health effects of stress, many of which are mediated by cortisone. To aid his research, Muglia developed a line of genetically modified mice where receptors for cortisone, which are found throughout the body, could be selectively eliminated in individual cell types.
By crossbreeding their genetically modified mouse lines, researchers produced a line of mice whose bone-dismantling osteoclasts lacked cortisone receptors. When researchers gave cortisone to these mice, the bone-weakening effects of the drugs were blocked.
In addition, scientists found that cortisone inhibits the ability of osteoclasts to dismantle old bone in genetically normal mice. This blockage might seem to leave bones free to retain their strength, but with the regular skeletal renewal process stopped, bones will weaken dramatically from aging and stress. Dampening of osteoclast activity may also cause a chain reaction that slows activity of bone-building osteoblasts.
“We now have an idea of what’s happening from a viewpoint of 1,000 feet up or so,” says Teitelbaum, comparing the new insight to sighting a highway from an airplane window. “Now we’ll start looking more closely at the molecular mechanisms involved to see if we can generate therapeutic targets.”

Not shortly after Roger Maris record was broken, another baseball player, Jason Giambi and various other athletes were either suspected of, or proven to have, taken anabolic steroids. Again, Congress convened a hearing, and just as they did the first time in 1990, they did not determine that steroids were a danger, but rather that the danger was more in protecting professional sports organizations. The updated statute has been updated to proscribe pro-hormones also The definition of an anabolic steroid as defined currently in the United States under (41)(A) is that "anabolic steroid" means any drug or hormonal substance, chemically and pharmacologically related to testosterone (other than estrogens , progestins, corticosteroids, and dehydroepiandrosterone (7).

Why do steroids cause high blood pressure

why do steroids cause high blood pressure

Not shortly after Roger Maris record was broken, another baseball player, Jason Giambi and various other athletes were either suspected of, or proven to have, taken anabolic steroids. Again, Congress convened a hearing, and just as they did the first time in 1990, they did not determine that steroids were a danger, but rather that the danger was more in protecting professional sports organizations. The updated statute has been updated to proscribe pro-hormones also The definition of an anabolic steroid as defined currently in the United States under (41)(A) is that "anabolic steroid" means any drug or hormonal substance, chemically and pharmacologically related to testosterone (other than estrogens , progestins, corticosteroids, and dehydroepiandrosterone (7).

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